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Science Digest

Dendritic cells: The key in the battle against HIV

By: Silvia Tosolini As finding a cure for HIV feels like a maze of locked doors, dendritic cells (DCs) emerge as the master key, unlocking the path to finding new treatment possibilities. HIV (human immunodeficiency virus) is a virus that infects the body’s immune system. Presently, there is no effective cure: once people have it,…

April 23, 20240Comments

ByBasti

Science Digest

From puzzle pieces to personalized medicine: how biomarkers tailor cancer therapy

Each person’s cancer has a unique combination of pieces in their puzzle. Partly due to the complexity of everyone’s genetic profile, it is challenging to develop effective one-size-fits-all therapy that targets all the cells within the tumour. Therefore, it has been suggested that treatment should be tailored to individual patients based on the specific characteristics…

March 1, 20240Comments

ByBasti

Extended communication Science Digest

A Novel Strategy to Improve Peptide Based Cancer Vaccines through Molecular Mimicry

Cancer remains a leading cause of mortality worldwide. The therapeutic options to treat cancer are often limited, which reduces the chance to successfully treat patients. To tackle this health problem, interventions are developed such as immunotherapies to target or influence the immune system. For example, cancer vaccines that are potentially able to initiate anti-tumour responses.

February 7, 20240Comments

ByJenna Pfeifer

Extended communication Science Digest

Of Mice and Men

By: Milo Molleson From house mouse to laboratory mouse The relationship between humans and mice has a long and captivating history. The house mouse, scientifically known as Mus musculus domesticus, has shared our narrative since its beginning; eating our grain and scurrying around our floors at night since before we left our nomadic lifestyles…

January 11, 20240Comments

ByBasti

Science Digest

mRNA circularization: a means to the two ends

Looking back at mankind’s history, we can see how the concept of circularization influenced the development of our society. Wheels, for example, are one of the most important first human inventions. Yet the concept of circularity is also prevalent naturally in biology. Molecules such as RNA, proteins, and nucleotides are more stable when circularized. But…

December 13, 20230Comments

ByBasti

Science Digest

A history of the RNA world hypothesis

Scientists have been speculating for over 50 years about RNA’s role at the beginning of life. They debate that before depending on DNA, primitive cells relied on RNA. This so-called RNA world would have existed some 4 billion years ago. But could primitive molecules have really depended on RNA before DNA?

November 8, 20230Comments

ByBasti

Science Digest

Drug repurposing: the solution might be closer than we think

When Sars-CoV-2 spread at the beginning of 2020, scientists started screening libraries full of drugs for possible treatments. This was the moment when the general public was introduced to drug repurposing.

October 24, 20230Comments

ByBasti

Science Digest

The Promise of Precision Medicine for Motor Recovery after Stroke

Precision medicine can be seen as tailoring a suit. Just a tailor takes individual measurements from an individual to ensure a good fit, precision medicine incorporates a patient´s genetic, environmental, and lifestyle factors to develop targeted treatments.

September 28, 20230Comments

ByBasti

Science Digest

An ‘unwanted journey’: how the immune microenvironment may contribute to breast cancer

DCIS is a potential breast cancer precursor lesion that occurs in 20-25% of diagnosed breast cancers. The risk factors for DCIS include obesity, lifestyle choices such as smoking, and rarely familial mutation such a BRCA mutations. Not every DCIS progresses to an invasive disease.

August 20, 20230Comments

ByBasti

Science Digest

A cellular railway in motion

Cilia are highly specialised structures that belong to the list of ancestral eukaryotic compartments together with nuclei and mitochondria. They protrude from the surface of nearly all human cells, acting as cellular antennae, sometimes more than one on each cell. Some cilia are involved in motility where they are found in specialised epithelia to facilitate…

August 9, 20230Comments

ByMadison Carr

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